Informasjon om | Engelsk ordet MACROCYCLIZATION

Eksempler på bruk av MACROCYCLIZATION i en setning

• The design of class A peptidomimetics often involves macrocyclization strategies as for example in stapled peptides.
• alt=A macrocyclization: a 1,5-pentanedithiol terminus attacks the butadiene tail of a 1-substituted 2,4-pentadien-2-yl aryl ketone.
• The ligand is prepared from diethylene triamine as follows by macrocyclization using ethyleneglycol ditosylate.
• Borylation of this material followed macrocyclization under Suzuki–Miyuara cross-coupling with an equivalent of the diiodide produced macrocycles in low yields which could be separated by column chromatography.
• Macrocyclizations have also been employed to form peptoid based macromolecular cages, the specific methodology utilizes a one pot synthesis to form steroid-aryl hybrid cages using two- and three-fold Ugi type macrocyclization reactions.

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