Anagrammer & Oplysninger om | engelsk ord BCRS

Eksempler på brug af BCRS i en sætning

• Junctional diversity occurs during recombination and serves to further increase the diversity of BCRs and TCRs.
• BCRs have distinctive binding sites that rely on the complementarity of the surface of the epitope and the surface of the receptor, which often occurs by non-covalent forces.
• These phosphatases inhibit activation of molecules involved in cell signaling, most commonly by binding to activating receptors including TCRs, BCRs and FcRs.
• Once an adaptive response has been mounted against one type of flagellin, or if a previous encounter has left the adaptive immune system ready to deal with one type of flagellin, switching types renders previously high affinity antibodies, TCRs, and BCRs ineffective against the flagella.
• Chiorazzi and his colleagues have demonstrated that: CLL cells are responsive to the signals from the internal microenvironment, specifically, those delivered by the B-cell antigen receptor (BCR) leading to leukemic cell proliferation and maturation or death; BCR-induced signals are likely delivered by common self-antigens and are mediated through sets of BCRs of remarkably similar amino acid structure; patients with CLL segregate into two subgroups based on BCR structure that differ dramatically in the clinical outcome; CLL cells proliferate and die in vivo at rates higher than originally appreciated.

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