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Horwitz was also first to synthesize stavudine (d4T) and zalcitabine (ddC) - two other reverse-transcriptase inhibitors used in the treatment of HIV patients.
Zalcitabine (2′-3′-dideoxycytidine, ddC), also called dideoxycytidine, is a nucleoside analog reverse-transcriptase inhibitor (NRTI) sold under the trade name Hivid.
is a Japanese virologist famous for his role in discovery of the anti-HIV drug zidovudine (AZT) as well as other anti-AIDS drugs including didanosine (ddI) and zalcitabine (ddC).
During the first years of the AIDS epidemic, he co-developed zidovudine (AZT), didanosine (ddI), and zalcitabine (ddC), which were the first effective drugs licensed for the treatment of AIDS.
With his colleagues, he conducted the first clinical trials of zidovudine (AZT), didanosine (ddI), zalcitabine (ddC), and lamivudine (3TC).
Jerome Horwitz, Wayne State University School of Medicine Professor of Internal Medicine and Karmanos Cancer Institute researcher; synthesized the first drug approved for the treatment of AIDS and HIV infection, Zidovudine; synthesized Zalcitabine (ddC) and Stavudine (d4T), the third and fourth drugs approved to treat AIDS.

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