Synonymer & Informasjon om | Engelsk ordet COFACTOR

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Eksempler på bruk av COFACTOR i en setning

• Cytochromes are redox-active proteins containing a heme, with a central iron (Fe) atom at its core, as a cofactor.
• In the description of protein structure, in particular in the Protein Data Bank file format, a heteroatom record (HETATM) describes an atom as belonging to a small molecule cofactor rather than being part of a biopolymer chain.
• Lysine 69 on ornithine decarboxylase (ODC) binds the cofactor pyridoxal phosphate to form a Schiff base.
• Two pathways have been proposed based on models that differ in the proximity of the iron to the pterin cofactor and the number of water molecules assumed to be iron-coordinated during catalysis.
• An inactive enzyme without the cofactor is called an apoenzyme, while the complete enzyme with cofactor is called a holoenzyme.
• Hauge as the third redox cofactor after nicotinamide and flavin in bacteria (although he hypothesised that it was naphthoquinone).
• Cytochromes P450 (P450s or CYPs) are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases.
• With B12 as an enzymatic cofactor, it is also synthesized from propionyl CoA, the odd-numbered fatty acid, which cannot undergo beta-oxidation.
• Thiamine pyrophosphate is a cofactor that is present in all living systems, in which it catalyzes several biochemical reactions.
• This observation reinforces that the Rossmann structural motifs found in NAD(+)-dependent dehydrogenases can have a dual function working as a nucleotide cofactor binding domain and as a ribonuclease.
• Nicotinamide adenine dinucleotide phosphate, abbreviated NADP or, in older notation, TPN (triphosphopyridine nucleotide), is a cofactor used in anabolic reactions, such as the Calvin cycle and lipid and nucleic acid syntheses, which require NADPH as a reducing agent ('hydrogen source').
• Each FeMo cofactor is covalently linked to the α subunit of the protein by one cysteine residue and one histidine residue.
• Factor I requires a C3b-binding protein cofactor such as complement factor H, CR1, or membrane cofactor of proteolysis (MCP or CD46).
• In the mathematical field of graph theory, Kirchhoff's theorem or Kirchhoff's matrix tree theorem named after Gustav Kirchhoff is a theorem about the number of spanning trees in a graph, showing that this number can be computed in polynomial time from the determinant of a submatrix of the graph's Laplacian matrix; specifically, the number is equal to any cofactor of the Laplacian matrix.
• Protein S, a vitamin K-dependent physiological anticoagulant, acts as a nonenzymatic cofactor to activate protein C in the degradation of factor Va and factor VIIIa.
• Betaine, sold under the brand name Cystadane among others, is indicated for the adjunctive treatment of homocystinuria, involving deficiencies or defects in cystathionine beta-synthase (CBS), 5,10-methylene-tetrahydrofolate reductase (MTHFR), or cobalamin cofactor metabolism (cbl).
• It requires NADPH as a cofactor for this reduction, and may involve the activity of cytochrome-P450 oxidoreductase.
• Covalently or non-covalently bound FMN is a cofactor of many enzymes playing an important pathophysiological role in cellular metabolism.
• Although sodium-dependent transporters for vitamin C exists, it is present mainly in specialized cells whereas the glucose transporters, most notably GLUT1, transport DHA in most cells, where recycling back to ascorbic acid generates the necessary enzyme cofactor and intracellular antioxidant, (see Transport to mitochondria).
• The debate of whether enterokinase was a cofactor or enzyme was resolved by Kunitz, who showed that the activation of trypsinogen by enterokinase was catalytic.

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